Firstly, it depends where it is and how much you are buying it for.
e.g. if it is for land value - then who cares about a building report like this.
You have highlighted bubbling paint on a ceiling - no big deal really
and $16K for a new roof......Look it may or may not need a new roof, but what really gets on my goat are building reports that are self promoting the inspector's own building company to fix "faults" discovered.
In my experience, many of these "quotes" are 3 times the price of a different contractor. If you proceed, I'd be getting 3 quotes.
In general terms, if I saw a report like this though, I would probably walk away - yes. But then again, I would not have ordered a report on a place like this - I can see bubbly paint, undulating floors and dates on HWS's for myself.